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herbalife 的消息!!!
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最近很多身边的朋友都进了这个转销叫 herbalife，我被他们说到有点心动所以就上网找关于herbalife 的消息，结果我看到了这篇文章是来自http://www.bloomberg.com/apps/ne ... fer=columnist_evans
Bloomberg Columnists
Nobel Prize Winner Didn't Disclose Herbalife Contract
Dec. 8 (Bloomberg) -- Louis Ignarro, who won a Nobel Prize for Medicine in 1998, endorsed a diet supplement for the heart sold by Herbalife International Inc. in exchange for royalties and then touted the ingredients in a scientific journal, without disclosing his financial interest to the publication.
Ignarro's consulting company received at least $1 million as its share of sales of Herbalife's Niteworks between June 2003 and September 2004, according to a filing with the Securities and Exchange Commission. The bottles sell for $90 each for a month's supply and display Dr. Ignarro's signature and Nobel Laureate status on the label.
``He's a paid consultant, so it should have been disclosed,'' said Marcia Angell, editor in chief of the New England Journal of Medicine in 1999 and 2000, now a senior lecturer on ethics at Harvard Medical School in Cambridge, Massachusetts. ``He had an interest in the substance he was evaluating.''
Herbalife pays Ignarro's consulting firm -- Hermosa Beach, California-based Healthwell Ventures LLC -- a share of Niteworks revenue ``sold with the aid of Dr. Ignarro's consulting, promotional or endorsement services,'' Herbalife wrote in a Dec. 2 SEC filing.
Herbalife has 1 million distributors in 59 countries with reported 2003 revenue of $1.16 billion.
Ignarro, 63, is the featured speaker in a one-hour Los Angeles based-Herbalife promotional video in which he claims Niteworks protects against heart disease, strokes, Alzheimer's and other diseases.
Hearts of Mice
The Nobel Prize winner didn't return telephone calls to his office and to the public relations department of the University of California at Los Angeles, where he teaches. Herbalife spokeswoman Barbara Henderson said the company won't comment, on advice from its lawyers, because it's planning an initial stock sale to the public.
His article, which appeared in the June 8 issue of the Proceedings of the National Academy of Sciences, described positive effects on the hearts of mice fed vitamins C and E, and arginine, an amino acid that produces nitric oxide in the body. All of those are in the Herbalife product.
Ignarro didn't disclose his Herbalife ties to the journal, according to Bridget Coughlin, managing editor of the Washington- based publication. ``There is indeed a conflict of interest that should have been included in this article,'' she said. ``There's a financial disclosure that should have been made.''
She said the journal has decided to issue a correction.
`They Jumped the Gun'
Ignarro formed Healthwell, the consulting company, in January 2003 with David Brubaker to receive royalties from Herbalife, according to state corporation records. Brubaker, 58, said in an interview that he estimates Herbalife has sold $50 million of Niteworks.
Brubaker said Herbalife pays Healthwell 1 percent of Niteworks sales revenue, and it received an advance against royalties in 2003.
Ignarro shared the Nobel Prize for discoveries about nitric oxide's function in the cardiovascular system. Pharmacologist Robert Furchgott, 88, who won the 1998 Nobel Prize with Ignarro for his own, independent research on nitric oxide, said in an interview that Ignarro's claims about Herbalife's effectiveness are improperly founded.
``They jumped the gun,'' he said. ``I haven't seen any properly controlled studies. It just seems to me a mouse model isn't transferable to humans.''
Sued in 1985
Herbalife spends less than $2 million each year on research and development, according to its prospectus filed with the SEC on Dec. 2.
The company, previously named Herbalife International, was sued by the California attorney general in 1985 for making false claims about its products. It settled the suit in 1986 for $850,000, agreeing not to make misleading statements. It didn't admit wrongdoing.
Mark Hughes, who started the company in 1980, served as Herbalife chairman and chief executive officer until 2000, when he died from an overdose of alcohol and antidepressants, according to the Los Angeles coroner.
Michael Johnson, who became CEO of Herbalife in April 2003, was an executive at Walt Disney Co. for 17 years before joining Herbalife. He was president of its Walt Disney International unit when he departed.
IPO This Month
He didn't answer written questions, referring comment to the company spokeswoman.
Herbalife has hired Merrill Lynch & Co. and Morgan Stanley, both based in New York, to raise as much as $193 million in an initial public offering later this month. Herbalife is incorporated in the Cayman Islands, with its headquarters in Los Angeles.
UCLA summarized the journal article in a May news release. Vitamins C and E, taken with arginine, along with moderate exercise, significantly reduce the risk of heart disease, the release said.
The release didn't name Herbalife and didn't say Ignarro is a paid company consultant. He is a professor of pharmacology at the university's school of medicine.
``It shows that supplements work well even in the absence of exercise,'' Ignarro was quoted as saying in the release, which recommended humans take dietary supplements. ``What's good for mice is good for humans.''
UCLA Conflict
Angell, the Harvard ethics lecturer, said UCLA had the responsibility to include Ignarro's financial arrangement with Herbalife in its news release. ``It seems an elementary conflict of interest,'' she said.
Roxanne Moster, director of media relations for UCLA Health Sciences, said the university doesn't research potential conflicts. ``We rely on our faculty members to let us know if there is a conflict,'' she said.
Former New England Journal editor Angell said Ignarro needs more than mouse studies to support his claims. ``There's a way to find out if it works in humans,'' by conducting clinical trials on people, she said. ``Until you do the trial, you don't know. There's a lot more work to do. You can't assume it will work for people.''
Herbalife markets Niteworks as a food supplement, so the Food and Drug Administration doesn't require it to be tested for safety or efficacy. Herbalife hasn't disclosed the results of any human testing of Niteworks.
``I think with the sort of money they're raking in, they could have done some human studies,'' said Ignarro's co-Nobel Prize winner Furchgott.
Clinical Studies
U.S. Senator Richard Durbin, an Illinois Democrat, said dietary supplement companies will twist facts to sell products. ``The actions attributed to Herbalife are yet another example of how the dietary supplement industry is the Wild West of the American health sector -- complete with medicine shows,'' he said.
Ignarro's consulting company partner Brubaker, a trustee of the University of Southern California in Los Angeles, sells Herbalife products from his house in Hermosa Beach. He said their consulting company is spending more than $150,000 to fund a clinical trial on the effectiveness of Niteworks.
``Mice are a good indication of the benefit of nitric oxide,'' Brubaker said. ``But it goes without saying that human studies are closer to the real world.''
Brubaker said he was aware of Ignarro's article in the medical journal. ``I don't know why it wouldn't have been disclosed,'' Brubaker said. ``Maybe it would have been an oversight on his part.''
Session in Las Vegas
Ignarro's video was taped during a training session for hundreds of company distributors at Herbalife's Las Vegas Extravaganza in June 2003 at the Mandalay Bay Resort. The video was streamed on Brubaker's Herbalife distributor Web site until yesterday. The video has since been removed.
``Guess what -- no more heart disease,'' Ignarro said on the tape. ``This is the nitric oxide story. The nitric oxide that is generated by this product is a vasodilator. It lowers the blood pressure. That's a good thing.''
Ignarro also said: ``I really think that soon there will be no heart disease. I really believe that.''
His Nobel Prize co-winner Furchgott said unproven claims like these shouldn't be used to sell the product to the public. ``I'm worried that Lou has gone into making a big thing of it before it's been thoroughly shown by controlled studies,'' Furchgott said.
Furchgott said he regrets Ignarro has become a pitchman for an unproven product, linked to their shared prize. ``That's sad,'' he said. ``Sometimes I get angry. Right now, I'm just sorry.''
To contact the reporter on this story: David Evans in Los Angeles at davidevans@bloomberg.net
Last Updated: December 8, 2004 11:38 EST
我并不是想要在这里批评些什么，只是在我个人观点觉得很大的 refusing! |
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发表于 10-1-2009 01:16 AM
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回复 1# 饼干之家 的帖子
Bloomberg专栏作家
诺贝尔奖优胜者没有透露Herbalife合同
12月。 8 (Bloomberg) -- 路易斯Ignarro， 1998年赢取一次诺贝尔奖为医学，支持补充营养为Herbalife卖的心脏International Inc. 以交换皇族然后招徕雇客成份在一个学报，不用透露他的金融权益对出版物。
Ignarro的咨询公司接受了$1至少百万作为Herbalife的Niteworks销售它的份额在2003年6月和2004年9月之间，根据屑子与SEC。 瓶为$90卖每为一个月的供应并且显示博士。 Ignarro的署名和诺贝尔奖得奖人状态在标签。
“他是一位受雇用的顾问，因此应该透露了它”，在概念在剑桥，马萨诸塞总编辑说Marcia Angell，新英格兰医学学报的1999年和2000年，现在一位资深讲师在哈佛医学院。 “他在他评估的物质上有兴趣。”
Herbalife支付Ignarro的咨询公司 -- Hermosa海滩，基于加利福尼亚的Healthwell冒险LLC -- Niteworks收支份额“在博士的帮助下卖了。 Ignarro的咨询的，增进或者背书服务， " Herbalife在12月写。 2 SEC屑子。
Herbalife有1百万经销商在59个国家与报告的2003年收支$1.16十亿。
Ignarro， 63，是特色报告人在他要求Niteworks保护免受心脏病、冲程、Alzheimer的和其他疾病的一小时洛杉矶基于的Herbalife增进录影。
老鼠的心脏
诺贝尔奖优胜者没有退回电话到他的办公室和到加州大学的公共关系部门在洛杉矶，他教。 Herbalife女发言人巴巴拉Henderson说公司不会评论，对忠告从它的律师，因为它计划最初的股票销售对公众。
他的文章，出版于国家科学院行动的6月8日问题，描述了正面作用对哺养的老鼠的心脏维生素C和E和氨基胍基戊酸，在身体生产氧化一氮的氨基酸。 所有那些在Herbalife产品。
Ignarro没有透露他的Herbalife领带对学报，根据Bridget Coughlin，基于华盛顿的出版物的管理编辑。 “在这篇文章应该包括的利害冲突”，她的确说。 “有应该做了的财务状况的披露。”
她说学报决定发布更正。 |
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发表于 10-1-2009 01:20 AM
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回复 1# 饼干之家 的帖子
他们跳跃Gun
Ignarro被形成的Healthwell，咨询公司，于2003年1月与大卫Brubaker从Herbalife接受皇族，根据国有企业纪录。 Brubaker， 58，在采访说他估计Herbalife卖了$50百万Niteworks。
Brubaker说Herbalife支付Healthwell Niteworks销售收入的1%， 2003年，并且它接受了前进反对皇族。
Ignarro分享了诺贝尔奖为关于氧化一氮的作用的发现在心血管系统。 药物学家罗伯特Furchgott， 88，赢取1998年诺贝尔奖与Ignarro为他自己，对氧化一氮的独立研究，在采访说Ignarro的要求关于Herbalife的有效率不正当地建立。
“他们过早行动”，他说。 “我未看任何适当地受控制研究。 它似乎对我模型不是可转移的对人的老鼠。"
起诉1985年
Herbalife在研究与开发上在12月每年花费少于$2百万，根据它的内容说明书归档与SEC。 2.
公司，早先命名Herbalife国际， 1985年由加利福尼亚检察长起诉为提出错误要求关于它的产品。 1986年它解决了衣服为$850,000，同意不做引入歧途的声明。 它没有承认不道德的行为。
标记休斯， 1980年建立公司，担当Herbalife主席和首席执行官直到2000年，当他死了于酒精和抗抑郁剂药剂过量，根据洛杉矶验尸官。
迈克尔・约翰逊，在2003年4月成为Herbalife CEO，是执行委员在Walt Disney Co。 17年在加入Herbalife之前。 当他离去了，他是它的华特・迪斯尼国际单位的总统。
IPO这个月
他没有回答书面问题，参见评论公司女发言人。
Herbalife聘用了马里尔・林曲& Co。 并且摩根Stanley，在纽约根据的两个，培养多达$193百万在原始股公开出售本月末。 Herbalife在开曼群岛在洛杉矶被合并，与它的总部。
加州大学洛杉矶分校在a 5月新闻发布总结了期刊文章。 维生素C和E，采取与氨基胍基戊酸，与适度锻炼一起，极大减少心脏病的风险，说的发行。
发行没有命名Herbalife，并且没有认为Ignarro是一位受雇用的公司顾问。 他是药理教授在大学的医学院。
“它显示补充甚而在没有锻炼时运作好”， Ignarro被引述了作为说在发行，推荐人作为饮食补充。 “什么为老鼠是好为人是好”。 |
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发表于 10-1-2009 01:22 AM
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回复 1# 饼干之家 的帖子
加州大学洛杉矶分校冲突
Angell，哈佛概念讲师，认为加州大学洛杉矶分校在它的新闻发布有责任包括Ignarro的财政安排与Herbalife。 “它似乎一基本利害冲突”，她说。
Roxanne Moster，媒介联系的主任为加州大学洛杉矶分校健康科学，说大学不研究潜在的冲突。 “我们依靠我们的大学教学人员告诉我们是否有冲突”，她说。
前新英格兰杂志编辑Angell更比老鼠研究说Ignarro需要支持他的要求。 “有方式通过进行临床试验发现，如果它运作在人”，在人，她说。 “直到您做试验，您不知道。 更大量有要做的工作。 您不可能假设它为人将运作。"
Herbalife销售Niteworks作为食物补充，因此粮食与药物管理局不要求它为安全或效力被测试。 Herbalife未透露其中任一人测试的结果Niteworks。
“我认为以他们倾斜的类金钱，他们可能做了一些人的研究”， Furchgott说Ignarro的co诺贝尔得奖者。 |
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发表于 10-1-2009 01:26 AM
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回复 1# 饼干之家 的帖子
临床研究
美国。 理查・ Durbin，伊利诺伊民主党参议员，说饮食补充公司将扭转事实卖产品。 “行动归因于Herbalife是另外例子的怎样饮食补充产业是狂放的在美国健康区段西边 -- 完成以医学展示”，他说。
Ignarro的咨询公司伙伴Brubaker，南加州大学的委托人在洛杉矶，在Hermosa海滩卖Herbalife产品从他的房子。 他说他们的咨询公司在Niteworks的有效率花费超过$150,000资助一次临床试验。
“老鼠是氧化一氮的好处的一个好征兆”， Brubaker说。 “但不言而喻那个人学习是离真实世界较近。”
Brubaker说他知道Ignarro的文章在医疗学报。 “我不知道为什么它不会被透露”， Brubaker说。 “可能它将是失察在他的part.”
会议在拉斯维加斯
Ignarro的录影录音了在一次训练期间为数百公司经销商在Herbalife的拉斯维加斯狂妄剧在2003年6月在曼德勒海湾手段。 录影在Brubaker的Herbalife经销商网站流出了直到昨天。 从那以后去除了录影。
“猜测什么 -- 没有其他心脏病”， Ignarro在磁带没有认为。 “这是氧化一氮故事。 是由这个产品引起的氧化一氮是血管舒张剂。 它降低血压。 那是一件好事。"
也说的Ignarro ： “我真正地认为很快将没有心脏病。 我真正地相信那。如
不应该用于这些卖产品对公众， "他的诺贝尔奖co优胜者Furchgott说未经证明的要求。 “我担心楼进入做一件大事它，在它由受控研究之前周到地显示了”， Furchgott说。
Furchgott说他后悔Ignarro成为了一个摊贩为一个未经证明的产品，连接与他们共有的奖。 “是哀伤的”，他说。 “有时我生气。 现在，我公正抱歉。"
与记者联系在这个故事： 大卫Evans在洛杉矶在davidevans@bloomberg.net
最近更新： 2004年12月8日11:38 EST |
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发表于 10-1-2009 01:31 AM
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发表于 10-1-2009 01:57 AM
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