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如下。。今天拿到化验报告。。不是很会读。。有谁可帮帮忙看看吗?
Test: Detection of EGFR gene mutation (exon 18, 19, 20, 21) by PCR and sequencing.
Result: None of the mutations listed below were detected in exons 18, 19, 20 and 21 of EGFR gene.
Method: DNA was extracted from the sample. Mutations in exons 18, 19, 20 and 21 of the EGFR gene were searched for using PCR amplification followed by bi-directional sequencing.
Comments: The mutations we screened include those found in
Exon 18 G-> T(nt 2155) G719/C; G->A(nt 2155) G719S
Exon 19 15bp del (nt 2235-2249) Cd 746-750
15bp del (nt 2236-2250) Cd 746-750
12bp del (nt 2240-2251) Cd 747-751 and insertion of Serine
18bp del (nt 2240-2257) Cd 747-753 and insertion of Serine
24bp del (nt 2254-2277) Cd 752-759
9bp del (nt 2239-2247) Cd 747-749 and nt 2248 G-> C (A750P)
18bp del (nt 2238-2255) Cd 747-752 and nt 2237 A-> T (E746V)
Exon 20 G->T (nt 2303) S7681; C-> T (nt 2369) T790M
Exon 21 T-> G (nt2573) L858R; T->A (nt 2582) L861Q
Mutations other than those listed above are not included in this investigation. |
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